In early game (Hands 1-4), go for 3 of a kind or 4 of a kind and place them into the upper section.

You should NOT fill in 4’s, 5’s, and 6’s unless you have three or more of the said dices.

Example
If you get 6-6-6-x-x or 6-6-6-6-x, place them into the upper section to secure the 35 score bonus in the upper section.